Table of Contents  
LETTER TO THE EDITOR
Year : 2013  |  Volume : 6  |  Issue : 3  |  Page : 346  

Kartagener's syndrome


Department of Medicine, Padmashree Dr. D.Y. Patil Medical College, Hospital and Research Centre, Dr. D.Y. Patil Vidyapeeth, Pune, Maharastra, India

Date of Web Publication5-Jul-2013

Correspondence Address:
Anunay Agarwal
Department of Medicine, Dr. D.Y. Patil Medical College, Pune, Maharastra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-2870.114664

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How to cite this article:
Satpathy P K, Diggikar P M, Agarwal A. Kartagener's syndrome. Med J DY Patil Univ 2013;6:346

How to cite this URL:
Satpathy P K, Diggikar P M, Agarwal A. Kartagener's syndrome. Med J DY Patil Univ [serial online] 2013 [cited 2019 Dec 14];6:346. Available from: http://www.mjdrdypu.org/text.asp?2013/6/3/346/114664

Sir,

We read with interest the case report of Kartagener's syndrome (KS) reported by Potdar et al. [1] Dextrocardia in the chest radiograph raises the possibility of KS and further workup as 20-25% of Situs inversus is associated with the primary ciliary dyskinesia (PCD). [2] This article does not have the photograph of chest X-ray of the patient even though it is referred to in the text. This autosomal recessive disorder presenting at the age of 60 years indicate a very mild phenotype. Four PCD loci, which are responsible for structural abnormalities of dynein arms of cilia, have been identified. They are DHAH 5 on chromosome 5p15; CILD2 on 19q, 16p12, 15q13-15; DNA11 on 9p13-21; DNAH11 on 7p15. [3] The association of KS with diffuse Bronchiolitis over and above bronchiectasis have been reported from Japan and India. [4],[5]

(In the case report by Potdar et al., [1] chest X-ray has been mentioned to have revealed dextrocardia while computed tomography of chest confirming dextrocardia has been illustrated. The editors appreciate the additional insights provided by the authors of this Letters to the Editor).

 
  References Top

1.Potdar PV, Nayak MM, Chitnis A. Kartagener's syndrome. Med J Dr. DY Patil Univ 2012;5:158-60.  Back to cited text no. 1
    
2.Casey B. Two rights make a wrong: Human left-right malformations. Hum Mol Genet 1998;7:1565-71.  Back to cited text no. 2
    
3.Mitchison H, Salathe M, Leigh M, Carson JL. Primary ciliary dyskinesia. Encyclopedia of Respiratory Medicine. 5 th ed., Vol. 3. Boston: Elsevier Ltd.; 2006. p. 487-8.  Back to cited text no. 3
    
4.Homma S, Kawabata M, Kishi K, Tsuboi E, Narui K, Nakatani T, et al. Bronchiolitis in Kartagener's syndrome. Eur Respir J 1999;14:1332-9.  Back to cited text no. 4
    
5.Mittal V, Shah A. Situs inversus totalis: The association of Kartagener's syndrome with diffuse bronchiolitis and azoospermia. Arch Bronconeumol 2012;48:179-82.  Back to cited text no. 5
    




 

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