ORIGINAL ARTICLE |
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Year : 2014 | Volume
: 7
| Issue : 3 | Page : 326-331 |
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Histopathological and cytological correlation of tumors of breast
Sushma Yalavarthi1, Ramamurti Tanikella2, Shailaja Prabhala2, Uma Shankar Tallam2
1 Department of Pathology, Mamata Medical College, Khammam, Andhra Pradesh, India 2 Department of Pathology, Kamineni Institute of Medical Sciences, Andhra Pradesh, India
Correspondence Address:
Sushma Yalavarthi Department of Pathology, Mamatha Medical College, Khammam, Andhra Pradesh India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/0975-2870.128975
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Background :0 With the advent of fine needle aspiration cytology (FNAC), the approach to diagnosis and management of breast lesions has been revolutionized. Its accuracy in many situations can approach that of histopathology in providing an unequivocal diagnosis. Aim :0 The aim of this study is to examine the cytological details in aspirated smears from lumps in the breast and to evaluate the role of FNAC in improving the quality of diagnosis by comparing with histopathological features. Materials and Methods: Over a period of 2 years, 334 aspirations, including 16 bilateral were performed. Suppurative and inflammatory lesions and gynecomastia were excluded from the total aspirates. A total of 56 cases were followed-up by histopathologic examination. Results: Cytohistologic correlation was 73.68%, 42.85%, 94.44% for fibroadenoma, fibrocystic disease and duct cell carcinoma respectively. False positives were observed in proliferative lesions. No false negative cases observed. The sensitivity of the fine needle aspiration (FNA) procedure was 100%, specificity, 88.5% and the predictive value of a positive result was 84%. Conclusion: Proliferative lesions may be misinterpreted as malignancy in FNA without complete clinical and mammographic details. |
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