CASE REPORT
Year : 2016  |  Volume : 9  |  Issue : 2  |  Page : 250-253

A presacral mass in a patient with thalassemia intermedia: A case report and review of the literature


1 Department of Pathology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
2 Colorectal Research Center, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence Address:
Mohammad Hossein Anbardar
Department of Pathology, Shiraz Medical School, Shiraz University of Medical Sciences, P. O. Box: 71345-1864, Shiraz
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-2870.177677

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Extramedullary hematopoiesis (EMH) is defined as the production of the myeloid and erythroid elements outside the bone marrow. It is usually a compensatory mechanism of the myeloid and erythroid production due to increased breakdown or diminished production of erythrocytes. Presacral EMH is an extremely rare condition, and there is a limited number of case reports published in the literature. A 39-year-old female patient as a known case of thalassemia intermedia presented with lower abdominal pain. A computerized tomography scan showed a large presacral mass, associated with bone destruction. The patient was admitted for exploratory laparotomy with suspicion to malignant lesions, but the final pathological diagnosis was EMH. It should be considered in differential diagnosis of mass-like lesions in the presacral area in patients with predisposing factors such as thalassemia, although there were malignant features such as bone destruction in imaging studies. Preoperative diagnostic tools such as fine needle aspiration and biopsy could help us to render the definite diagnosis and prevent unnecessary operation.


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