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LETTER TO THE EDITOR
Year : 2017  |  Volume : 10  |  Issue : 2  |  Page : 215  

Dyke-Davidoff-Masson syndrome-unanswered questions


1 Department of Neurology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India
2 Department of Obstetrics and Gynaecology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India

Date of Web Publication14-Mar-2017

Correspondence Address:
Khichar Purnaram Shubhakaran
House No. E-22/13, Umaid Hospital Campus, Geeta Bhawan Road, Jodhpur - 342 001, Rajasthan
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/MJDRDYPU.MJDRDYPU_282_16

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How to cite this article:
Shubhakaran KP, Khichar RJ. Dyke-Davidoff-Masson syndrome-unanswered questions. Med J DY Patil Univ 2017;10:215

How to cite this URL:
Shubhakaran KP, Khichar RJ. Dyke-Davidoff-Masson syndrome-unanswered questions. Med J DY Patil Univ [serial online] 2017 [cited 2017 Oct 21];10:215. Available from: http://www.mjdrdypu.org/text.asp?2017/10/2/215/202113

We read an interesting case report of Dyke-Davidoff-Masson syndrome (DDMS) by Jilowa and colleagues.[1] Here, we would like to share our experience:

  1. The eminent authors have written that DDMS is usually diagnosed in early childhood but rare cases are diagnosed in young adults as the author's patient was diagnosed at the age of 25 years.[1] The authors have written “age of presentation depends on the time of occurrence of the brain insult and often clinical features may not be evident till adolescence.”[2] In this study, the mean age was 26.84 ± 9.71 as range of 8–42 years.[3] Here, the awareness of patient and relatives, competence of treating pediatric or other physician, and suspicion of the syndrome are more important besides presentations for diagnosing the condition at appropriate time and its management
  2. Authors have said it to be more common in males [1] as in our case series study of 32 patients in which 21 patients were males [3]
  3. It is said to have slight left hemispheric preponderance as in the author's patient,[1] and so is in our case series [3]
  4. The authors treated the patient with carbamazepine [1] which is a better drug than phenytoin as we have observed in our study where phenytoin was more associated with side effects and poor response [3]
  5. As the authors have said that “the condition needs to be differentiated from Basal ganglia germinoma, Sturge-Weber syndrome, Fishman syndrome, and Rasmussen encephalitis.”[1] We in a cohort of 31 patients found three patients of Rasmussen encephalitis [3]
  6. Of course, case reports are welcome, now it is time for case series [4] so as to use for Cochrane review and to streamline the various etiologic factors, clinical presentations, treatment strategies, and preventive interventions. Along with this, modern functional neuroimaging will also be of useful as exemplified by some case studies.[5]


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Conflicts of interest

There are no conflicts of interest.

 
  References Top

1.
Jilowa CS, Meena PS, Jain M, Sharma KK. Dyke-Davidoff- Masson syndrome: A rare case report. Med J DY Patil Univ 2016;9:730-2.  Back to cited text no. 1
  [Full text]  
2.
Lee JH, Lee ZI, Kim HK, Kwon SH. A case of Dyke-Davidoff-Masson syndrome in Korea. Korean J Pediatr 2006;49:208-11.  Back to cited text no. 2
    
3.
Bhargava A, Bhushan B, Kasundra G, Shubhakaran K, Guruprashad SP, Basavaraj B. Dyke-Davidoff-Masson syndrome: A study of clinicoradiological variability in hemiplegia, hemiatrophy and epilepsy patients. CHRISMED J Health Res 2014;1:187-93.  Back to cited text no. 3
  [Full text]  
4.
Shubhakaran, Bhushan B. Dyke-Davidoff-Masson Syndrome: Time to revisit case series. J Assoc Physicians India 2015;63:96.  Back to cited text no. 4
    
5.
Gupta R, Joshi S, Mittal A, Luthra I, Mittal P, Verma V. Magnetic resonance imaging depiction of acquired Dyke-Davidoff-Masson syndrome with crossed cerebro-cerebellar diaschisis: Report of two cases. J Pediatr Neurosci 2015;10:294-6.  Back to cited text no. 5
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