RT - Journal TY - JOUR A1 - Sakaria, Rishika A1 - Shah, Ira A1 - Bhatnagar, Sushmita T1 - Neonatal hepatitis with herpes simplex YR - 2016/5/1 JF - Medical Journal of Dr. D.Y. Patil University JO - Med J DY Patil Univ SP - 397 OP - 399 VO - 9 IS - 3 UL - https://journals.lww.com/mjdy/pages/default.aspx/article.asp?issn=0975-2870;year=2016;volume=9;issue=3;spage=397;epage=399;aulast=Sakaria;t=5 DO - 10.4103/0975-2870.182521 N2 - We report two cases of neonatal hepatitis with herpes simplex virus (HSV) infection. Whether the HSV infection was the cause of hepatitis, or merely associated with it is not clear. While, in the first case, resolution could not be achieved despite high-dose antiviral treatment with acyclovir and liver transplant had to be advised; in the second case, there was complete resolution of the disease without antiviral therapy. Role of acyclovir in these children needs further assessment. ER -