Year : 2013  |  Volume : 6  |  Issue : 3  |  Page : 250-253

Lipid profile and electrocardiographic changes in thyroid dysfunction

Department of Medicine, Padmashree Dr. D. Y. Patil Medical College, Hospital and Research Centre, (Dr. D.Y. Patil Vidyapeeth), Pune, Maharashtra, India

Correspondence Address:
Prasanna K Satpathy
Department of Medicine, Padmashree, Dr. D.Y. Patil Hospital, (Dr. D.Y. Patil Vidyapeeth) Pimpri, Pune - 411 018, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0975-2870.114647

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Background: The study was designed to explore lipid profile and electrocardiographic changes associated with thyroid dysfunctions. Materials and Methods: A total of 72 patients of thyroid dysfunction having either hypothyroidism or hyperthyroidism were investigated with lipid profiles and electrocardiogram (ECG). Hypothyroids with ST-T ECG changes who were symptomatic for coronary artery disease were subjected to further investigations and were benefitted by either medical therapy or revascularization procedures following coronary angiography. Results: Out of the 72 patients, 44 (61.11%) were suffering from hypothyroidism, while hyperthyroidism was present in 28 (38.89%). Female:male ratio was 4.5:1. Maximum number of hypothyroid patients (73%) had either borderline high (36.6%) or high (36.36%) serum cholesterol; 67.86% of the 28 hyperthyroid patients had serum cholesterol levels <200 mg%. In hypothyroidism, ST segment and T wave ECG changes (ST-T changes) were the commonest electrocardiographic findings. Conclusion: Hypothyroidism was associated with high serum cholesterol levels whereas maximum patients with hyperthyroidism had normal serum cholesterol levels. Correlation was found between ST-T changes on ECG and high serum cholesterol levels in hypothyroidism.

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