Table of Contents  
COMMENTARY
Year : 2014  |  Volume : 7  |  Issue : 1  |  Page : 101-102  

Capgras syndrome


Department of Psychiatry, Mahatma Gandhi Missions Medical College, Kamothe, Navi Mumbai, Maharashtra, India

Date of Web Publication10-Dec-2013

Correspondence Address:
Darpan Kaur
8/187, M.H.B., Om-Lamba Society, Opposite Bhakti-Dham Mandir, Sion-Chunabhatti, Mumbai-400 022, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Kaur D. Capgras syndrome. Med J DY Patil Univ 2014;7:101-2

How to cite this URL:
Kaur D. Capgras syndrome. Med J DY Patil Univ [serial online] 2014 [cited 2021 Sep 17];7:101-2. Available from: https://www.mjdrdypu.org/text.asp?2014/7/1/101/122806


  Introduction Top


Delusional misidentification syndrome includes Capgras syndrome, Fregoli syndrome, inter-metamorphosis, and the syndrome of subjective doubles. Until the past decade, these syndromes were considered extremely rare; however, an increasing number of cases are now being reported in literature. [1]


  Epidemiology Top


Capgras syndrome can occur primarily in the setting of a schizophrenic illness, affective disorder, and organic illness. [2] It is often associated with medical illness and should signal the treating clinician to investigate for organic conditions. [3] Capgras syndrome is relatively rare, occurring predominantly in the context of schizophrenia, and is traditionally considered to have its origins in the theory of psychodynamic conflict. Recent literature, however, highlights the estimated prevalence between 25 and 40% in the content of organic disorders such as dementia, head trauma, epilepsy, and cerebrovascular disease. [4]


  Clinical Features Top


The person has a delusion that one or a few highly familiar people have been replaced by impostors who are physically very similar to the original/s. The patient may acknowledge that the double and known person look alike, but maintains the belief that the significant person, in psychological terms, is absent.


  Typology Top


Capgras syndrome and the other syndromes are grouped together because they often co-occur and interchange, and their basic theme is the concept of the double (sosie). They are sometimes classified into hypoidentification syndrome (Capgras syndrome) and hyperidentifications (Fregoli syndrome, intermetamorphosis, and the syndrome of subjective doubles). [2]


  Neurocognitive Overlay Top


The syndrome of Capgras is not only a dysfunction in facial recognition but in recognizing a person globally. The sense of feeling of familiarity is absent due to the inability to integrate successive memories about a person along episodic experiences. This hypothetically can generate delusional doubles in accordance to the patient's needs or drives.


  Neurobiological Overlay Top


Capgras delusion arises from the failure in reconciling information about identification of the person and its associated emotions by the disconnection between frontal lobes and right temporo-limbic regions (hippocampus), in addition to bilateral frontal damage. Delusions are commonly associated with right hemisphere lesions because of the impairment of several functions such as self-monitoring, reality monitoring, memory, and feelings of familiarity. [5] Lesions are usually bifrontal and/or right hemispheric in delusion misidentification syndromes when neurological comorbidity occurs. Negative effects of right hemisphere injury impair self-monitoring, ego boundaries, and attaching emotional valence, and familiarity to stimuli. Cognitive style of categorization of the left hemisphere leads it to invent a duplicate or impostor to resolve conflicting information. Delusions in Capgras syndrome generally result from right hemisphere lesions; however, it is the left hemisphere that is deluded. [6]


  Neurophysiological Overlay Top


Nowadays, event-related potentials, especially auditory P300 component, form a useful tool for providing information regarding the functions of the brain in Capgras syndrome. [1]


  Current Research Scenario Top


Various types of misidentification syndromes have been recognized in recent literature. However, they tend to be discussed as case reports or as a whole. This may be primarily due to a small number of cases encountered by each researcher. [7] Most of our knowledge about Capgras syndrome derives from single case studies and small series of cases usually from diagnostically heterogeneous groups. [8]


  Clinical Implications Top


Existing literature highlights the occurrence of Capgras syndrome in other nonpsychiatric organic conditions. It is extremely important to be aware of organic conditions that can present like Capgras syndrome. Relevant investigations and imaging may be performed to rule out organic basis. The clinician must consider standard psychopharmacological and psychotherapeutic interventions for the same.

 
  References Top

1.Warchala A, Krupka-Matuszczyk I. Delusional misidentification syndrome. Wiad Lek 2006;59:702-6.  Back to cited text no. 1
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2.Christodoulou GN, Margariti M, Kontaxakis VP, Christodoulou NG. The delusional misidentification syndromes: Strange, fascinating, and instructive. Curr Psychiatry Rep 2009;11:185-9.  Back to cited text no. 2
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3.Dohn HH, Crews EL. Capgras syndrome: A literature review and case series. Hillside J Clin Psychiatry 1986;8:56-74.  Back to cited text no. 3
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4.Edelstyn NM, Oyebode F. A review of the phenomenology and cognitive neuropsychological origins of the Capgras syndrome. Int J Geriatr Psychiatry 1999;14:48-59.  Back to cited text no. 4
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5.Madoz-Gúrpide A, Hillers-Rodríguez R. Capgras delusion: A review of aetiological theories. Rev Neurol 2010;50:420-30.  Back to cited text no. 5
    
6.Devinsky O. Delusional misidentifications and duplications: Right brain lesions, left brain delusions. Neurology 2009;72:80-7.  Back to cited text no. 6
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7.Nishida H, Shinbo Y, Kuramitsu M, Motomura H. One possible classification of the delusional misidentification syndromes and its developmental, regressive understandings. Seishin Shinkeigaku Zasshi 1996;98:533-54.  Back to cited text no. 7
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8.Silva JA, Leong GB. The Capgras syndrome in paranoid schizophrenia. Psychopathology 1992;25:147-53.  Back to cited text no. 8
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  In this article
Introduction
Epidemiology
Clinical Features
Typology
Neurocognitive O...
Neurobiological ...
Neurophysiologic...
Current Research...
Clinical Implica...
References

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