CASE REPORT
Year : 2014  |  Volume : 7  |  Issue : 1  |  Page : 70-72

Olanzapine induced tardive dyskinesia

Rudraprosad Chakraborty1, Arunima Chatterjee2, Suprakash Chaudhury3
1 Consultant Psychiatrist, Berhampore Mental Hospital, Berhampore, West Bengal, India
2 Department of Physiology, Burdwan Medical College, Burdwan, West Bengal, India
3 Department of Psychiatry, Pravara Institute of Medical Sciences (Deemed University), Rural Medical College, Loni, India

Correspondence Address:
Suprakash Chaudhury
Prof. and Head, Department of Psychiatry, Pravara Institute of Medical Sciences (Deemed University), Rural Medical College, Loni - 413 736
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-2870.122790

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Olanzapine is considered to have significantly less risk of tardive dyskinesia (TD) compared to first generation antipsychotics. We describe two patients who developed TD after prolonged use of olanzapine. Both the patients received no medications prior to the treatment with olanzapine. They neither received any other medication along with olanzapine nor any injectible antipsychotics. In one patient, TD improved completely after withdrawal of olanzapine and treatment with clozapine, but recurred after a retrial of olanzapine. In the other patient, reduction of dose of olanzapine was tried without any success. Despite a substantially lower risk than first generation antipsychotics, TD is not entirely absent with olanzapine.


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