ORIGINAL ARTICLE
Year : 2014  |  Volume : 7  |  Issue : 2  |  Page : 152-155

Study of ionic calcium in maternal and cord blood and baby's blood at 48-h age


Department of Pediatrics, Padmashree Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India

Correspondence Address:
Neelam Deshpande
Navpinnac Kanchanganga Co-Op. Hsg. Society, H-102, D. P. Road, Aundh, Pune - 411 007, Maharashtra
India
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Source of Support: Padmashree Dr. D. Y. Patil University, Pimpri, Pune., Conflict of Interest: None


DOI: 10.4103/0975-2870.126321

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Background: Newborns undergo a physiological nadir in serum calcium levels by 24-48 h of age. We have compared the ionic calcium levels in serum of normal as well as high-risk pregnant mothers before delivery, in cord blood of newborns and in neonates at 48 h of age. Materials and Methods: This is a prospective study of 500 pregnant women. One hundred and twenty-two pregnant women did not receive any calcium supplementation antenatally while 378 pregnant women received calcium supplementation antenatally. Results: A statistically significant correlation was found between ionic calcium levels in mothers and in cord blood in the study population and preterm and term babies (coefficient of correlation, r = 0.83, 0.86 and 0.83, respectively). Ionic calcium in baby's blood at 48-h age better correlated with cord blood (r = 0.67) than with maternal blood (r = 0.51). With calcium supplementation antenatally, the mean values for serum calcium of maternal blood, cord blood and baby's blood at 48 h of age were higher than those without antenatal calcium supplementation. Conclusions: Antenatal calcium supplementation may prevent hypocalcemia in the newborn thus preventing neonatal morbidity.


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