CASE REPORT
Year : 2014  |  Volume : 7  |  Issue : 4  |  Page : 494-496

Distal renal tubular acidosis and quadriparaesis in Sjögren's syndrome: A cunning congregate


1 Professor and Head, Department of Medicine, Bharati Vidyapeeth University Medical College and Bharati Hospital, Pune, Maharashtra, India
2 Postgraduate student, Department of Medicine, Bharati Vidyapeeth University Medical College and Bharati Hospital, Pune, Maharashtra, India
3 Intern, Bharati Vidyapeeth University Medical College and Bharati Hospital, Pune, Maharashtra, India

Correspondence Address:
Arundhati G Diwan
Flat No. 16, Laxmi Abhishek, Laxmi Park Colony, Navi Peth, Pune - 411 030, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-2870.135282

Rights and Permissions

Sjögren's syndrome (SS) is a chronic autoimmune disease, chiefly affecting the exocrine glandular function of salivary glands and lacrimal glands. Rarely, it involves the kidneys, central and peripheral nervous system, muscloskeletal apparatus and lungs. We report a rare constellation of SS with distal renal tubular acidosis and quadriparaesis in a young female. History of quadriparaesis was acute, with rapid progression. Supplementary treatment for severe hypokalemia was instituted at the earliest, lest the patient develop respiratory muscle weakness. Concomitantly, metabolic acidosis with alkaline urine was suspected and subsequently investigated. Eventually, this was attributed to impaired renal acidification of urine in the distal tubules. History of dryness of eyes and mouth since 6 months justified salivary gland biopsy. The results yielded a lymphocytic infiltrative pathology strongly favoring SS. The patient benefited from prompt potassium replacement therapy and had complete resolution over the next week. Supportive treatment for predictable manifestations was continued along with potassium supplements.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2219    
    Printed50    
    Emailed1    
    PDF Downloaded167    
    Comments [Add]    

Recommend this journal