CASE REPORT |
|
Year : 2015 | Volume
: 8
| Issue : 4 | Page : 543-546 |
|
Amelanotic melanoma of the nasal mucosa: A rare case report
Bharat Bhushan Dogra, Ashwani Kandari, Mahendra Kataria, Archana Buch
Department of Surgery, Padmashree Dr. D. Y. Patil Medical College Hospital and Research Centre, Pimpri, Pune, Maharashtra, India
Correspondence Address:
Bharat Bhushan Dogra Department of Surgery, Dr. D. Y. Patil Medical College Hospital, Pimpri, Pune - 411 018, Maharashtra India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/0975-2870.160834
|
|
Melanomas develop due to malignant transformation of melanocytes, which are derived from the neuroectoderm. Although the majority of melanomas are cutaneous, they occasionally arise from extra-cutaneous tissues as well which contain melanocytes, such as uvea, leptomeninges, or the mucosa. Melanomas can be melanotic or amelanotic. Approximately, 15-20% of all malignant melanomas arise in head and neck region and over 80% of these involve the skin. Mucosal malignant melanomas are very rare and may affect the upper aero-digestive tract (UADT). Their incidence is approximately as low as 0.5-3% of all malignant melanomas. Majority of noncutaneous head and neck malignant melanomas affect the ocular origin and only 6-8% originate in the mucous membranes of the UADT. Nasal mucosal melanomas account for <1% of all melanomas and <5% of all nasal tract neoplasms. The incidence of amelanotic melanomas (AMs) has been estimated to be between 1.8 and 8.1% of all melanomas. We present a case of 62-year-old lady presenting with epistaxis and a mass in left nasal cavity, diagnosed as AM and managed by wide local excision and primary reconstruction in our institution.
|
|
|
|
[FULL TEXT] [PDF]* |
|
|
|