Table of Contents  
LETTER TO THE EDITOR
Year : 2016  |  Volume : 9  |  Issue : 3  |  Page : 416-417  

Poroid hidradenoma: An unusual presentation


Department of Pathology, Hind Institute of Medical Sciences, Barabanki, Uttar Pradesh, India

Date of Web Publication17-May-2016

Correspondence Address:
Nidhi Awasthi
521/177, Bhairon Prasad Marg, Bara Chand Ganj, Lucknow, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-2870.168000

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How to cite this article:
Awasthi N. Poroid hidradenoma: An unusual presentation. Med J DY Patil Univ 2016;9:416-7

How to cite this URL:
Awasthi N. Poroid hidradenoma: An unusual presentation. Med J DY Patil Univ [serial online] 2016 [cited 2022 Dec 2];9:416-7. Available from: https://www.mjdrdypu.org/text.asp?2016/9/3/416/168000

Sir,

The term "poroma" refers to a group of benign cutaneous adnexal neoplasms with "poroid" or terminal ductal differentiation. Four histopathologic variants have been identified depending on location of the tumor cells: Hidradenoma simplex, eccrine poroma, dermal duct tumor and poroid hidradenoma. [1],[2],[3] Recent studies have shown a common histogenesis for all these variants. [4]

A 45-year-old male presented to the surgical outpatient department with a gradually increasing swelling of 1-year duration, over right lower anterior abdominal wall. There were no other associated symptoms. On examination, there was a 3 cm × 3 cm, mobile, nontender, erythematous lump arising from anterior abdominal wall of right iliac fossa. His past medical and family history were unremarkable. A clinical diagnosis of infected sebaceous cyst was made. The nodular swelling was excised under local anesthesia and was sent for histopathological examination.

Macroscopic examination showed a skin covered soft tissue mass measuring 3 cm × 2.5 cm × 1.5 cm. Cut surface showed a sub-epidermal, well-circumscribed, solid grayish white tumor with multiple small cystic foci [Figure 1]. Microscopic examination revealed a well-circumscribed, lobulated, intra-dermal, solid-cystic tumor, with no apparent connection to the overlying epidermis [Figure 2]. The tumor was composed of, small and dark staining poroid cells having round to oval nuclei, indistinct nucleoli with scant eosinophilic cytoplasm [Figure 3] and cuticular cells having round nuclei, distinct nucleoli with abundant eosinophilic cytoplasm. Cuticular cells showed evidence of ductal differentiation at places [Figure 4]. Focal areas showed glandular structures lined by columnar to cuboidal cells with clear cell change at places, cystic spaces filled with eosinophilic material, [Figure 1] irregular ectatic vessels and stromal infiltration by lymphocytes and plasma cells. Histomorphological findings were compatible with poroid hidradenoma. The postoperative period was uneventful and the patient was doing well after 2 months of surgery.
Figure 1: Gross appearance

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Figure 2: Low power examination: (H & E, ×100), intra-dermal, solid-cystic tumor. Cystic spaces containing eosinophilic material shown by white arrows

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Figure 3: H & E, ×400 showing poroid cells

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Figure 4: H & E, ×400 showing cuticular cells with ductal differentiation

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Poroid hidradenoma is an uncommon variant of Poromas described by Abenoza and Ackerman in 1990, [1],[2],[3] occurring over a wide age range from 17 to 91 years, [2] with a peak in the seventh decade. It presents clinically as a solitary, circumscribed, intra-dermal nodule. Histopathologically, these are hybrid lesions, showing cytological characteristics of poromas with poroid and cuticular cells [3] and architectural features of hidradenoma, which is an intra-dermal, solid-cystic tumor. [1] Some reports have stressed on the role of fine needle aspiration cytology in the diagnosis of these solid-cystic tumors. [5] To date, few cases of poroid hidradenoma have been reported in the literature. [1],[2]

To conclude, Poroid hidradenoma is an uncommon benign adnexal tumor which can present clinically as a cystic lesion. It should be considered in the differential diagnosis of cutaneous solid-cystic lesions preoperatively, so that adequate surgical excision is done and recurrences are prevented.

 
  References Top

1.
Goksugur N, Yilmaz F. Poroid hidradenoma. Acta Dermatovenerol Croat 2011;19:122-3.  Back to cited text no. 1
[PUBMED]    
2.
Koo CL, Chang H. Poroid hidradenoma. Tzu Chi Med J 2009;21:181-2.  Back to cited text no. 2
    
3.
Chen CC, Chang YT, Liu HN. Clinical and histological characteristics of poroid neoplasms: A study of 25 cases in Taiwan. Int J Dermatol 2006;45:722-7.  Back to cited text no. 3
    
4.
Battistella M, Langbein L, Peltre B, Cribier B. From hidroacanthoma simplex to poroid hidradenoma: Clinicopathologic and immunohistochemic study of poroid neoplasms and reappraisal of their histogenesis. Am J Dermatopathol 2010;32:459-68.  Back to cited text no. 4
    
5.
Hoshida Y, Hanai J, Matsushita N, Yonekawa M, Kobayashi Y, Kawakami H, et al. Poroid hidradenoma. Report of a case with cytologic findings on fine needle aspiration. Acta Cytol 1999;43:471-4.  Back to cited text no. 5
    


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4]



 

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