AU - Chari, Vangipuram AU - Paul, Arnab TI - Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placebo PT - ORIG DP - 2016 Jan 1 TA - Medical Journal of Dr. D.Y. Patil University PG - 61-65 VI - 9 IP - 1 4099- https://journals.lww.com/mjdy/pages/default.aspx/article.asp?issn=0975-2870;year=2016;volume=9;issue=1;spage=61;epage=65;aulast=Chari;type=0 4100- https://journals.lww.com/mjdy/pages/default.aspx/article.asp?issn=0975-2870;year=2016;volume=9;issue=1;spage=61;epage=65;aulast=Chari AB - Background: Postoperative sore throat (POST) is the most common airway-related complaint of patients after endotracheal intubation. Postextubation coughing during emergence from general anesthesia (GA) is an important problem. Objectives: To compare the effects of topical benzydamine hydrochloride and 2% lignocaine on reducing the incidence and severity of POST, hoarseness, and coughing after general endotracheal anesthesia. Materials and Methods: Patients were randomly allocated into three groups of 30 patients each. In Group B (topical benzydamine hydrochloride), Group L (2% lignocaine gel), Group N (normal saline) was applied to the cuffed endotracheal tube (ETT) before intubation. Results: The trend of the severity of sore throat, hoarseness of voice, and cough during the first 24 h after the GA in benzydamine recipients was significantly lower than the other two groups (P < 0.05). Conclusions: It was observed that the incidence of POST, hoarseness of voice, and cough was significantly less when cuff of ETT was lubricated with topical benzydamine hydrochloride as compared with 2% lignocaine gel.